References popup

The weeks shown in color represent the start and end points of chemical exposure for each study.

Study Results Study Details References

Results for Dioxin (TCDD)

Decreased body weights on post-natal days 7, 21 and 30

Subjects: C57BL/6 mice

Chemical: Dioxin (TCDD)

Low doses tested: 1.0 μg/kg bw

Route of administration: dissolved in corn oil and administered orally

Exposure duration: post-natal day 1 – post-natal day 4 (comparable to human prenatal development from approximately day 1 of week 15 to day 1 of week 21)

Age of measurement: post-natal days 7, 21, 30 and 60

Reference [PubMed Link]
Jin MH, Hong CH, Lee HY, Kang HJ, Han SW. 2010. Toxic effects of lactational exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) on development of male reproductive system: involvement of antioxidants, oxidants, and p53 protein. Environ Toxicol 25(1):1-8.
Study Results Study Details References

Results for Dioxin (TCDD)

Decreased body length on post-natal days 30 and 60

Subjects: C57BL/6 mice

Chemical: Dioxin (TCDD)

Low doses tested: 1.0 μg/kg bw

Route of administration: dissolved in corn oil and administered orally

Exposure duration: post-natal day 1 – post-natal day 4 (comparable to human prenatal development from approximately day 1 of week 15 to day 1 of week 21)

Age of measurement: post-natal days 7, 21, 30 and 60

Reference [PubMed Link]
Jin MH, Hong CH, Lee HY, Kang HJ, Han SW. 2010. Toxic effects of lactational exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) on development of male reproductive system: involvement of antioxidants, oxidants, and p53 protein. Environ Toxicol 25(1):1-8.