The weeks shown in color represent the start and end points of chemical exposure for each study.
Study Results | Study Details | References |
Results for Dioxin (TCDD)Decreased relative thymus weight at 0.3 μg/kg |
Subjects: Wistar rats Chemical: Dioxin (TCDD) Low doses tested: 0.3 or 3.0 μg/kg bw Route of administration: injected subcutaneously Exposure duration: gestational day 19 – single dose (comparable to human prenatal development from approximately day 1 of week 10 to day 1 of week 11) Age of measurement: 77 days of age |
Reference Korte M, Stahlmann R, Thiel R, Nagao T, Chahoud I, Vanloveren H, Vos JG, Neubert D. 1991. Resistance to trichinella-spiralis infection, induction of hepatic monooxygenases, and concentrations in thymus and liver in rats after perinatal exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin. Chemosphere 23(11-12):1845-1854. |