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At approximately day 1

Single positive T cells detectable in cord blood.

Reference [PubMed Link]

West LJ. 2002 Sep-Oct. Defining critical windows in the development of the human immune system. Hum Exp Toxicol 21(9-10):499-505.

At approximately day 1

First plasma cells found in fetal lymphoid tissue.


Williams CB. 2003. Development of the immune system. In Rudolph’s Pediatrics 21st Edition, Rudolph CD & Rudolph AM, Editors. New York: McGraw-Hill.