The weeks shown in color represent the start and end points of chemical exposure for each study.
|Study Results||Study Details||References|
Results for ChlorpyrifosIncreased cholesterol and triglyceride levels in males; increased insulin levels in non-fasted males
Subjects: Sprague-Dawley rats
Low doses tested: 1.0 mg/kg bw/d
Route of administration: dissolved in DMSO and injected subcutaneously
Exposure duration: post-natal day 1 – post-natal day 4 (comparable to human prenatal development from approximately day 1 of week 20 to day 1 of week 25)
Age of measurement: 110 days of age
|Reference [PubMed Link]
Slotkin TA, Brown KK, Seidler FJ. 2005. Developmental exposure of rats to chlorpyrifos elicits sex-selective hyperlipidemia and hyperinsulinemia in adulthood. Environ Health Perspect 113(10):1291-1294.