The weeks shown in color represent the start and end points of chemical exposure for each study.
|Study Results||Study Details||References|
Results for Bisphenol AIncreased time spent in diestrus; lack of corpora lutea and vaginal cornification at 4 weeks only
Subjects: CD-1 mice
Chemical: Bisphenol A
Low doses tested: 0.5 mg/kg bw/d
Other doses tested: 10 mg/kg bw/d
Route of administration: injected subcutaneously
Exposure duration: gestational day 15 – gestational day 18 (comparable to human prenatal development from approximately day 1 of week 7 to day 1 of week 11)
Age of measurement: from 4 to 16 weeks of age
|Reference [PubMed Link]
Nikaido Y, Yoshizawa K, Danbara N, Tsujita-Kyutoku M, Yuri T, Uehara N, Tsubura A. 2004. Effects of maternal xenoestrogen exposure on development of the reproductive tract and mammary gland in female CD-1 mouse offspring. Reprod Toxicol 18(6):803-811.